GENEALOGY-DNA-L Archives

Archiver > GENEALOGY-DNA > 2008-05 > 1209647967


From:
Subject: Re: [DNA] Counting the founders: the matrilineal genetic ancestryof the Jewi...
Date: Thu, 1 May 2008 09:19:52 EDT


Here's the abstract. The link to full text is

http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0002062

PLoS ONE. 2008 Apr 30;3(4):e2062.

Counting the founders: the matrilineal genetic ancestry of the jewish
diaspora.

Behar DM, Metspalu E, Kivisild T, Rosset S, Tzur S, Hadid Y, Yudkovsky G,
Rosengarten D, Pereira L, Amorim A, Kutuev I, Gurwitz D, Bonne-Tamir B, Villems
R, Skorecki K.

Molecular Medicine Laboratory, Rambam Health Care Campus, Haifa, Israel.

The history of the Jewish Diaspora dates back to the Assyrian and Babylonian
conquests in the Levant, followed by complex demographic and migratory
trajectories over the ensuing millennia which pose a serious challenge to unraveling
population genetic patterns. Here we ask whether phylogenetic analysis, based
on highly resolved mitochondrial DNA (mtDNA) phylogenies can discern among
maternal ancestries of the Diaspora. Accordingly, 1,142 samples from 14 different
non-Ashkenazi Jewish communities were analyzed. A list of complete mtDNA
sequences was established for all variants present at high frequency in the
communities studied, along with high-resolution genotyping of all samples. Unlike
the previously reported pattern observed among Ashkenazi Jews, the numerically
major portion of the non-Ashkenazi Jews, currently estimated at 5 million
people and comprised of the Moroccan, Iraqi, Iranian and Iberian Exile Jewish
communities showed no evidence for a narrow founder effect, which did however
characterize the smaller and more remote Belmonte, Indian and the two Caucasus
communities. The Indian and Ethiopian Jewish sample sets suggested local female
introgression, while mtDNAs in all other communities studied belong to a
well-characterized West Eurasian pool of maternal lineages. Absence of sub-Saharan
African mtDNA lineages among the North African Jewish communities suggests
negligible or low level of admixture with females of the host populations among
whom the African haplogroup (Hg) L0-L3 sub-clades variants are common. In
contrast, the North African and Iberian Exile Jewish communities show influence of
putative Iberian admixture as documented by mtDNA Hg HV0 variants. These
findings highlight striking differences in the demographic history of the widespread
Jewish Diaspora.

PMID: 18446216 [PubMed - in process]


**************
Need a new ride? Check out
the largest site for U.S. used car listings at AOL Autos.

(http://autos.aol.com/used?NCID=aolcmp00300000002851)

This thread: