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Archiver > GENEALOGY-DNA > 2005-08 > 1122909473


From: "William Curry" <>
Subject: Re: [DNA] 43 Marker I1a4 Haplotype
Date: Mon, 1 Aug 2005 09:17:53 -0600
References: <000a01c596a5$564a3040$71509045@Ken1>


I should have waited for you to answer my question before I asked it.
Thanks.
William

----- Original Message -----
From: "Ken Nordtvedt" <>
To: <>
Sent: Monday, August 01, 2005 8:28 AM
Subject: [DNA] 43 Marker I1a4 Haplotype


>I have received my 43 (44?) marker haplotype for a I1a4 (M227+) dna sample.
>The sample was from an Estonian and the extended haplotype measured by DNA
>Heritage.
>
> On essentially all the markers but two it looks like a normal I1a
> haplotype. At DYS426 which is an extremely slow mutating marker, however,
> it has 10 repeats instead of the usual 11 present in all haplogroup "I"
> haplotypes. I had previously found a population of 20 such haplotypes
> (with DYS426 = 10) in Sorenson database and a few in Ysearch as well. The
> pedigree distribution in Sorenson was strongly German and Russian-German
> with the addition of a couple Slovenians, a couple Danes, a Swede, and a
> Brazilian.
>
> The Rootsi paper found I1a4 haplotypes at a small percentage of I1a in
> Eastern Europe. But they only had 6 German haplotypes in their collection
> and 8 Dutch. They had a good Danish population but did not test them for
> M227. The only unusual feature of Rootsi's distribution of I1a4
> haplotypes is that they found none among their 60 I1a haplotypes from
> Sweden.
>
> Another unusual feature of my tested I1a4 haplotype is that it had a fifth
> DYS464 allele. They reported it 12,14,14,15,16 at 464. It will be
> interesting if this oddity is present in other I1a4 haplotypes along with
> the 10 at DYS426?
>
> Actually, I believe the odds are rather high that I1a4 is really a
> subclade of I1a1. So a P40 test will be done at Ethnoancestry when I get
> my sample back.
>
> Anyone with an I1a haplotype (8 repeats at DYS455) and also having the
> unusual 10 at DYS426 should be tested for M227 (I1a4) by Ethnoancestry.
>
> Ken
>
>
> ==============================
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