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From: "Roberta J. Estes" <>
Subject: RE: [DNA] Alaska Caveman Y haplogroup Q-M3*
Date: Mon, 1 Aug 2005 02:12:25 -0400
In-Reply-To: <001401c5965c$708cf210$5a66ba44@Roanne>


Jason Eshleman, the author, is one of the scientists who worked for
Ripan Mahli before he merged Trace Genetics with DNA Print.

Roberta

-----Original Message-----
From: [mailto:]
Sent: Monday, August 01, 2005 1:47 AM
To:
Subject: [DNA] Alaska Caveman Y haplogroup Q-M3*

Re: Ancient Native Am. DNA analyzed

From: http://www.palanth.com/forum/index.php?topic=792.new

The 1-page article in Nature is not very informative. Here is more
information, the abstract for the original presentation made to the
American
Association for the Advancement of Science meeting last month (mentioned
in
the Nature article), forwarded here here with permission of one of the
co-authors, Jason Eshleman.


Quote
Analysis of Ancient DNA from an Individual from Prince of Wales Island:
Implications for the Peopling of the New World, BRIAN M. KEMP, DAVID
GLENN SMITH, JASON ESHLEMAN, RIPAN S. MALHI, JOHN MCDONOUGH, E. DEBORAH
BOLNICK, JAMES DIXON, TIMOTHY H. HEATON, TERENCE FIFIELD, and ROSITA
WORL


Ancient mitochondrial and Y-chromosome DNA were successfully extracted
from the teeth of an individual dated to 9,880 ± 50 (CAMS- 32038) and
9,730 ± 60 (CAMS-29873) excavated from On Your Knees Cave (site
49-PET-408) on Prince of Wales Island in Southeast Alaska. d13C
values of 12.1 and 12.5% suggest a diet of marine foods, so the date
should be adjusted to c. 9,200 14C ybp. The mitochondrial DNA (mtDNA)
of this individual belongs to haplogroup D and the Y-chromosome to
haplogroup Q-M3*, which also confirms that the sex of the individual
was male. This individual's mitochondrial haplotype (based on his
hypervariable region I+II sequences) does not represent the basal
haplogroup D lineage, demonstrating that multiple founder lineages of
this haplogroup reached the New World. This haplotype matches or
closely matches published sequences of Native American mtDNA found in
populations of both North and South America, being found in
approximately 1% of living Native Americans. The known date associated
with this sample allows for the calibration of the molecular clock and
can be used to assess the accuracy of earlier estimates of the timing
of the peopling of the New World based on molecular diversity. This
sample also establishes a minimum date for the emergence of the M3
Y-chromosome mutation, which is believed to have occurred early during
the settlement of the New World.

I live in Ashland, OR. Wish I had known the meeting was being held
here!

Roanne


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